Statistical Methods in the Multi-Laboratory Validation of a PFAS Measurement Method

August, 2023
IDA document: 3000051
FFRDC: Systems and Analyses Center
Type: Documents
Division: Science and Technology Division , Science, Systems and Sustainment Division
Allyson M. Buytendyk, Katherine I. Fisher, Tyler J. Pleasant, Sara C. Runkel, Jay S. Shah, John J. Silk See more authors
This report documents the statistical analyses used to characterize the overall performance of the method used to measure per- and polyfluoroalkyl (PFAS) substances for a multilaboratory validation study. It highlights instances where statistical formulas used in the analysis differ from the Environmental Protection Agency’s guidance for new method approval, and it provides high-level observations about the environmental samples, PFAS, and labs derived from some of the datasets analyzed.