Statistical Methods in the Multi-Laboratory Validation of a PFAS Measurement Method

August, 2023
IDA document: 3000051
FFRDC: Systems and Analyses Center
Type: Documents
Division: Science and Technology Division
Authors:
Authors
Allyson M. Buytendyk; Katherine I. Fisher; Tyler J. Pleasant; Sara C. Runkel; Jay S. Shah; John J. Silk See more authors
This report documents the statistical analyses used to characterize the overall performance of the method used to measure per- and polyfluoroalkyl (PFAS) substances for a multilaboratory validation study. It highlights instances where statistical formulas used in the analysis differ from the Environmental Protection Agency’s guidance for new method approval, and it provides high-level observations about the environmental samples, PFAS, and labs derived from some of the datasets analyzed.