The Informatics Technology for Cancer Research (ITCR) Program is a trans-NCI grant program supporting investigator-initiated informatics technology development driven by critical needs in cancer research. Collaboration is an intentional hallmark of the ITCR program. The program is meant to function as a network, with investigators participating in annual meetings, monthly teleconferences, and working groups; a portion of award funds are reserved for collaborative activities, including efforts that integrate tools developed by individual teams. As part of an assessment conducted in advance of the decision whether and how to proceed with the program in the future, NCI tasked the IDA Science and Technology Policy Institute (STPI) in February 2018 to survey ITCR investigators with respect to collaborations within and among funded awards.